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As a widely applied antioxidant, N-acetylcysteine (NAC) affects redox regulation by replenishing GSH, reducing disulfide bonds in proteins or other molecules, or directly scavenging oxidants and is often used as a supplement that may help with various conditions [26]

A review and analysis of randomized controlled trials concluded that horse chestnut seed extract is an effective and safe short-term treatment for chronic venous insufficiency (Pittler 2012

1 Long-term exposure to heavy metals can lead to a range of health issues, including cognitive impairment, hormonal imbalances, poor immune function, kidney, liver, and brain damage, and even age-related chronic diseases such as cancer, heart disease, and neurodegenerative diseases

doi: 10.1186/1476-4598-13-258