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Inflammation can also be a complication of lithium, although less well known than its tubulotoxic effects

Mietus-Snyder ML, Shigenaga MK, Suh JH, Shenvi SV, Lal A, McHugh T, Olson D, Lilienstein J, Krauss RM, Gildengoren G, et al

Studies using mouse models with genetic ablation of TAK1 have demonstrated its essential role in preventing oxidative tissue injury in the epidermis and intestinal epithelium