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Initiation and Propagation of -Synuclein Aggregation in the Nervous System

In our hypothetical model, shown in Figure 5 , the decrease in CAT activity might have resulted in ROS accumulation, leading to lipid peroxidation and enzyme inactivation, which could in turn promote structural and functional damage to proteins and carbohydrates and modification or disruption of DNA structure ( Figure 5 Our study has demonstrated the potential of fungal allelochemicals in inhibiting weed growth through oxidative damage, contributing valuable insights to the limited literature on this topic

In some cases, doctors may recommend lifestyle changes alongside medical treatments, such as avoiding prolonged sitting or standing, which can exacerbate symptoms

2 Pathological role of ferroptosis in retinal diseases The retina is mainly composed of the inside out of retinal pigment epithelial cells (RPE), photoreceptor cells, horizontal cells, bipolar cells, node cells, amacrine cells, and retinal ganglion cells (RGC), as the key part of the vision with the functions that captures light and passes it to the brain (Hoon et al., 2014)