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Biochemical reports also demonstrated that enhanced oxidative stress, dysregulated apoptosis, and extensive inflammatory reactions mediated by overexpressed inflammatory factors [such as tumor necrosis factor (TNF-), interleukin 1 (IL-1), and interleukin 6 (IL-6)] were served as the underlying mechanisms for the occurrence of various CSD-relevant diseases (810)

doi: 10.3390/cancers12020305 65 MauteRXuJWeissmanIL

Approved Indications Methycobal is indicated for the treatment of peripheral neuropathies nerve damage causing symptoms such as numbness, tingling, burning, or pain, including diabetic peripheral neuropathy and for megaloblastic anaemia caused by vitamin B12 deficiency