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Description

Growth inhibition of human lung cancer cells via down-regulation of epidermal growth factor receptor signaling by yuanhuadine, a daphnane diterpene from daphne genkwa

Reactions were performed with 50 M RHKKAc, a fluorogenic peptide substrate from p53 residues 379382, 500 M NAD + co-substrate, and recombinant human SIRT-1 (NAD + -dependent) enzyme