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308 Abnormal intracellular calcium signaling could also impact various organelles such as the ER, mitochondria, and lysosomes

[DOI] [PubMed] [Google Scholar] 807.Lyall F, Gibson JL, Greer IA, Brockman DE, Eis AL, Myatt L

Additionally, supplementation may be necessary, especially for dogs with specific health conditions or those that are more susceptible to oxidative stress

A notable exception to this biosynthetic capability are the nematode Caenorhabditis elegans and other parasitic helminths, which are heme auxotrophs 25