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Editors-in-Chief: Giuseppe Argenziano Language: English Frequency: 4 issues/year eISSN: 2160-9381 Impact Factor 2025: 2.4 CiteScore 2025: 2.2 SJR 2025: 0.504 - SNIP 2025: 0.746 Indexed in: MedLine PubMed (NLM ID 101585990) 1989-ongoing

Six high-affinity IGFBPs (IGFBP-1 through IGFBP-6) actively regulate IGF bioavailability, receptor access, and tissue distribution [7]

Tesamorelins program was carried through a disciplined clinical development path by Theratechnologies, culminating in Phase 3 trials in HIV-associated lipodystrophy and FDA approval in November 2010