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Clinical Evidence Human Trials: A randomized, placebo-controlled study in obese adults demonstrated that AOD-9604 significantly reduced abdominal and total body fat over several weeks of treatment, without serious side effects Animal Studies: Preclinical studies in mice and rats showed that AOD-9604: Stimulated lipolysis Inhibited lipogenesis (formation of new fat) Prevented weight gain despite high-fat diets This dual actionenhancing fat breakdown and inhibiting fat formationpositions AOD-9604 as a potent tool for combating obesity

Their conjugation to 68 Ga or 64 Cu allowed in vivo visualization of CD38 + myeloma or lymphoma tumors in murine xenograft models [97, 111]

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This is a biphasic (hormetic) dose-response common with copper peptides and many other biological compounds