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Neurosci Lett 10(12):171174 Sonnewald U, Westergaard N, Schousboe A, Svendsen JS, Unsgard G, Petersen SB (1993) Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons

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The use of agents such as trientine and ammonium tetrathiomolybdate has been advocated, although results of long-term trials are awaited