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However, only pimitespib, an oral inhibitor developed by Taiho Pharmaceutical, was approved in Japan in 2022 for gastrointestinal stromal tumors, and it is currently the focus of a phase I study for the treatment of solid tumors in the EU and USA [7, 8]

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Its mode of action is especially advantageous for individuals with sensitive skin or those primarily seeking to diminish redness associated with AN (23, 24, 26)