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The aims of this study were to identify biomarkers that precisely reflect visual field defects and the loss of RGCs in human subjects, and to identify IOP-independent biomarkers of glaucoma in a validation study based on targeted metabolomics

Although direct evidence of trained immunity in clinical AD is still limited, transcriptional, epigenetic, and metabolic alterations observed in immune cells, including microglia, monocytes, and dendritic cells, from both patients and animal models are consistent with mechanisms underlying innate immune memory

This reduces dosing frequency and makes it easier for patients to stick to their treatment plan

Agric Biol Chem 45:21312132 Murata K, Miya T, Gushima H, Kimura A (1983) Cloning and amplification of a gene for glutathione synthetase in Escherichia coli B