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Studies on autophagy and various neurodegenerative diseases are summarized in Table 1

Homologous 1-Cys proteins are widely distributed throughout all kingdoms, and they have been described in archaea, bacteria, parasites, yeast, insects, mollusks, amphibians, birds and other orders (130) (Table I)

Prior studies have reported that active metabolites of fenofibrate can regulate metabolism, fatty acid synthesis, and other cellular processes disrupted by viral infections