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Although many studies have found a possible relationship between the gut microbiota and AD pathogenesis, the inconsistency and reproducibility of existing clinical results need to be addressed before clinical application

doi: 10.3389/fnut.2025.1682590 Received 19 August 2025 Accepted 30 September 2025 Published 15 October 2025 Volume 12 - 2025 Edited by Vincenzo Piccolo, University of Naples Federico II, Italy Reviewed by Yar Adona Snchez Nuo, University of Guadalajara, Mexico Angela Erna Rossato, University of the Extreme South of Santa Catarina, Brazil Updates Copyright 2025 Fatima, Khan, Shukla, Awaida, Li and Gushchina

RHBDF2 governs microglial neuroinflammation during cerebral ischemia-reperfusion injury and is positively regulated by the m6A reader YTHDF1