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We tested the hypothesis that diminished GSH in adult patients with uncontrolled type 2 diabetes is attributed to decreased synthesis and measured the effect of dietary supplementation with its precursors cysteine and glycine on GSH synthesis rate and oxidative stress

Studies consistently find that, compared with healthy controls, the -diversity (e.g., Shannon index, Chao1 index) of gut flora in liver disease patients is significantly reduced, and -diversity (community structure) shifts significantly, indicating that the gut microbial ecosystem tends toward simplification and disorder in disease states

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