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In laboratory microbial evolution experiments, different cells within the initial population dynamically expand and shrink their clone sizes by acquiring new mutations over multiple generations 5,6,7,8,9

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Plasma levels of iFABP were observed to be higher in patients with a severe form of ulcerative colitis compared to those with a mild form of the disease, and higher serum levels of iFABP were reported in celiac disease patients who had increased intestinal permeability compared to healthy controls (112), underlying that this protein might be used as an indicator of an extended inflammatory process (90)