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Description

HPF1 interacts with the PARP-1 catalytic domain and colocalizes with it at sites of DNA damage (8)

Regular stability testing ensures consistent results across multiple experiments

Conversely, under hypoxic conditions, phosphoglycerate mutase 5 (PGAM5) and ULK1 catalyze the dephosphorylation and phosphorylation of Ser13 and Ser17, respectively, thereby inducing mitophagy [19]