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Homocysteine: Genetics, High Homocysteine Levels, and Solutions Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. In Situ Lysosomal Cysteine Specific Targeting and Imaging during Dexamethasone Induced Apoptosis Analytical Chemistry Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells ScienceDirect

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