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doi: 10.1590/0001-3765201620150595 58 EmanueleE.OrsiP.BosoM.BrogliaD.BrondinoN.BaraleF.et al

Alcohol gets metabolized in the liver and during its metabolism, it generates free radicals

400,405 An inhibition in mitochondrial fusion, especially caused by the down-regulation of Mfn, is closely related to liver diseases due to an impairment in fatty acid oxidation, the TCA cycle, and glycolysis