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Prat G, Adan A, Sanchez-Turet M

E2 regulates mitochondrial biogenesis, dynamics and antioxidant defense through both genomic pathways [such as nuclear receptor-mediated regulation of peroxisome proliferator-activated receptor coactivator 1- (PGC-1)] and non-genomic mechanisms (such as membrane receptor signaling and mitochondrial DNA protection) (18)