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179 In NASH patients, ALR levels are significantly reduced, and this deficiency may contribute to disease progression

In another embodiment, an assay is a cell-based assay comprising contacting a cell expressing a membrane-bound form of NOVX protein, or a biologically-active portion thereof, on the cell surface with a test compound and determining the ability of the test compound to modulate (e.g., stimulate or inhibit) the activity of the NOVX protein or biologically-active portion thereof

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NQO1, a reductase that can maintain antioxidant forms of CoQ10, -tocopherol and ascorbic acid, plays an important role in maintaining antioxidant protection and inhibiting lipid peroxidation