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Use of antihistamine medications during early pregnancy and isolated major malformations

For the four-channel fluorescence images, 405-nm excitation with 405/488/561 triband emission filter, 488-nm excitation with 525/50 emission filter, 561-nm excitation with 605/70 emission filter, and 640-nm excitation with 700/75 emission filter were used with a quad band 405/488/561/640 dichroic mirror