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MOTS-c activates AMPK pathways that improve GLUT4 glucose transport, restoring cellular glucose uptake without the GI side effects of metformin.5 For adults managing prediabetes or metabolic syndrome, this is clinically significant

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Boxes represent the interquartile range (IQR) and whiskers extend to 1.5 the IQR or to the minimum and maximum values if no point exceeds that range

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10.1038/s41586-024-08350-8 Nature 90 JinL.LiD.AlesiG

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