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The accumulating data of animal experimentation involving interventions targeting ferroptosis are promising in terms of the perspective of the symptoms reversal and inhibition of the disease progression [238]

Rudman D, Sewell CW, Ansley JD: Deficiency of carnitine in cachectic cirrhotic patients

Although fatigue and fatigability essentially result from a central phenomenon (since MS is a disease of the central nervous system), there are some central al peripheral factors to take into consideration when exploring the phenomenology of fatigue