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Clinical PK data could not be obtained in the early stage of drug development, making this study an important reference for reducing the risk of human toxicity in phase I clinical design

78 (61%) and 51 (40%) patients were part of the minimal alcohol and moderate alcohol use groups respectively

(v) Finding genetic susceptibilities to metal toxicants, such as by using Drosophila models (178), could uncover predispositions to toxicant-induced neurological diseases and could aid in preventative measures by avoiding toxicant exposures