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DTP cells reversibility and dynamic nature make them a highly promising therapeutic target (39)

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Studies have shown that natural bioactive compounds from TCM (e.g., berberine, curcumin) contribute to synergistic anti-inflammatory and antioxidant effects, as well as enhanced drug-targeted delivery, while TCM formulations (e.g., Gegen Qinlian Decoction, Xilei San) exert holistic multi-target regulation by inhibiting key inflammatory pathways such as nuclear factor-kappa B (NF-B) and mitogen-activated protein kinase (MAPK), modulating gut microbiota composition, and restoring mucosal barrier function