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Description

We recently demonstrated increased CD38 expression in skin biopsies from patients with SSc, and correlation with clinical disease severity 24

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What is known is that murine B1 cells are metabolically inflexible in the absence of autophagy, as B1 cell numbers are reduced, fat metabolism transcripts are down-regulated, and compensatory uptake in glucose is minimized following conditional deletion of the autophagy gene Atg7 (96)