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The classic antidiabetic drug Metformin, besides controlling blood glucose, can activate the AMPK pathway, improve mitochondrial function, and indirectly enhance cellular antioxidant capacity, thereby conferring resistance to ferroptosis in reparative cells (89)

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An J-R, Su J-N, Sun G-Y et al (2022) Liraglutide alleviates cognitive deficit in db/db mice: involvement in oxidative stress, iron overload, and ferroptosis