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10.1371/journal.pone.0207374 216 NematisouldaraghD.KirshenbaumE.UzonnaM.KirshenbaumL.Rabinovich-NikitinI

Dysfunction of this system, often resulting from chronic stress or poor sleep quality, leads to the accumulation of toxic metabolites, which is a hallmark of neurodegenerative diseases

5 Aiming for 2028 launches with best-in-class ambition The strategic bet: patients want less frequent dosing, better tolerability, and therapies that fit real lifenot just clinical trial perfection