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Brookhuis SAM, et al

Moore A, Morris ID: The involvement of insulin-like growth factor-I in local control of steroidogenesis and DNA synthesis of leydig and non-leydig cells in the rat testicular interstitium

secondly, relative to other organs, the brain has lower levels of ROS scavenging enzymes and thirdly the brain is 60% fat a high proportion of which is unsaturated fatty acids that are highly susceptible to lipid peroxidation