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However, research still needed to determine the pathogenic impact of mitochondrial dysfunction in the development of PD and the underlying mechanisms involved

While these can contribute, they may not be the sole explanation

Physiol Mol Plant Pathol 62(6):333346 Shetty NP, Mehrabi R, Ltken H, Haldrup A, Kema GH, Collinge DB, Jrgensen HJL (2007) Role of hydrogen peroxide during the interaction between the hemibiotrophic fungal pathogen Septoria tritici and wheat

8.1.2 Pathway enrichment analysis Genomics analysis is complemented by pathway enrichment analysis, where the focus is shifted from single gene alteration to biological system-level alteration