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The effect of VB on promoting M1 polarization and suppressing OC progression is enhanced by AKT inhibition (using LY294002), but reduced by CCN1 overexpression

Vasquez-Vivar J, Shi Z, Tan S

57 In astrocytes, 5-HT has a strong effect on the 5-HT 2B receptor

Due to the late diagnosis, high metastatic potential, and resistance to chemoradiotherapy, patients who are diagnosed with PDA have a poor prognosis, with an overall 5-year survival rate of ~6% 2