is glutathione a stimulant Glutathione: Master Antioxidant and Detoxifier Glutathione! - PMC

Figure 1 The authors next explored which cell type is most sensitive to oxidative stress during the pathologic process of acute lung injury by detecting intracellular ROS levels with a fluorescent probe, and found that total ROS levels were significantly increased and the intracellular GSH/GSSG ratio was significantly decreased in macrophages in the hyperoxia-exposed group compared with the control group, and that Grx1 levels were significantly decreased in hyperoxia-exposed alveolar macrophages (AMs)

Carroll RC, Beattie EC, von Zastrow M, Malenka RC

However, some studies suggest that the generation of ROS does not seem to be necessary for elesclomol to exert its cytotoxicity

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