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Talking microbes: When gut bacteria interact with diet and host organs

Conclusion Good Clinical Practice plays a fundamental role in ensuring effective pharmacovigilance throughout the drug development lifecycle

Hanson M, Pleva J

It has been reported that betulinic acid can activate peroxisome proliferator-activated receptor coactivator 1 alpha (PGC-1), a key coactivator of FXR, in brown adipocytes [20, 21]