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Luteolin has been found as a strong inhibitor of numerous MMPs, including MMP-2, MMP-9, MMP-1, MMP-3, and MMP-13 [127]

10.1016/0263-7855(96)00018-5 26 KauppM.Von SchneringH

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In their review published in Endocrine Reviews , the authors state, The approximately 1000-fold lower Km of D2 than D1 [D2 is 1000 times more efficient] may give this enzyme a major advantage in terms of extrathyroidal T3 production