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Transcriptomic analysis of induced pluripotent stem cells (iPSCs) carrying an A53T SNCA mutation and a triplication discovered that the expression of mitochondrial function-related genes was perturbed (Zambon et al., 2019), which could explain the observed reduction in mitochondrial respiration, aberrant mitochondrial morphology, and decreased mitochondrial membrane potential

Research indicates that glutathione supplementation can reduce muscle damage, expedite recovery time, and enhance endurance levels

In contrast, GSH depletion drives M1 polarization, resulting in heightened secretion of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1 (Kwon et al., 2019)

Versus stimulant-based fat burners Many over-the-counter fat burners rely on stimulants like caffeine, synephrine, or more concerning compounds