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For suspected DVT particularly unilateral leg swelling with pain seek same-day assessment at an A&E or ambulatory care unit able to arrange urgent duplex ultrasound, in line with NICE NG158

Box: Hydroxocobalamin dosing schedule for the management of pernicious anaemia If no neurological involvement: Loading dose: 1,000 micrograms three times per week for two weeks Maintenance dose: 1,000 micrograms every two to three months If neurological involvement: Loading dose: 1,000 micrograms every other day until no further improvement Maintenance dose: 1,000 micrograms every two months Injections are usually administered at a GP surgery, although some patients can be taught to self administer[22]

10.1021/acschemneuro.0c00242 80 HulbertA

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