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Inhibition of amino acid metabolism selectively targets human leukemia stem cells

In the case of renal impairment, urinary elimination of carnitine increasing, endogenous synthesis decreasing, and poor nutrition as a result of disease-induced anorexia can result in carnitine deficiency

J., Bilgir, C., Ro, J

Based on data present in literature, necroptosis is increased in the lungs of COPD patients and its inhibition attenuates CS-induced emphysema, airway inflammation, and remodeling making this process an attractive candidate for COPD patients