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These transcriptomic findings demonstrate that Retatrutide facilitates the remodeling of dysfunctional adipose tissue by coordinately inhibiting pro-fibrotic and adhesion signals while reinstating pro-homeostatic gene programs, thereby counteracting the fibrotic effects of a high-fat diet

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14 The trial also showed Donanemab slowed cognitive decline by 35% and showed 39% lower risk of progressing to the next stage of the disease when compared to placebo