l-carnitine makes you poop | Linus Pauling Institute Kirkland Signature Healthy Weight Cat

The suggestion that increased BCAA levels could merely be a consequence of impaired insulin action is in accordance with the results from a recent mendelian randomization study [60], showing that insulin resistance drives higher plasma BCAA levels [60, 61]

Furthermore, the anti-obesity properties of carnitine might be attributed to its potential role in stimulating adipocyte lipolysis, through upregulating lipolytic gene expression, namely, hormone-sensitive lipase (HSL) (21), carnitine palmitoyl transferase Ia (CPT-Ia) (21), and acyl coenzyme A oxidase (ACO) (21), as well as attenuating adipogenesis in adipocytes through suppression of adipogenic gene expression, including peroxisome proliferator-activated receptor gamma (PPAR-) and adipose-specific fatty acid-binding protein (aP2) in adipose tissue (21)

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