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Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (2000)

Aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL1), which is the core protein of the biological clock, can be degraded through p62-mediated selective autophagy, leading to an increase in expression of Prolyl Hydroxylase Domain 1 (PHD1), promoting lipid peroxidation in cells and further promoting ferroptosis

Interestingly, the use of an alternative start codon in human preproinsulin mRNA can lead to the translation of a nonconventional insulin product and the generation of neoantigenic peptides thereof, which are targets of T cell-mediated autoimmunity in type 1 diabetes [44]