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The enhanced cocktails, CILy (CHIR+IDE1+Ly) and CIP (CHIR+IDE1+PD), significantly increased the expression of DE markers SOX17 and FOXA2, with CIP showing the highest efficiency, comparable to the traditional CA method

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Among the various regulated cell death (RCD) pathways, a novel formcuproptosishas recently emerged, uniquely triggered by disruptions in copper metabolism [2]

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