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Also, activation of TRPV1 in human CECs importantly contributes to the development of ocular inflammation in DED patients [32]

Acetyl-L-Carnitine (ALCAR) The modified version of L-carnitine, known as acetyl-L-carnitine, or ALCAR, has an acetyl group linked to it

The effects of l-carnitine supplementation on inflammatory factors, oxidative stress, and clinical outcomes in patients with sepsis admitted to the intensive care unit (ICU): study protocol for a double blind, randomized, placebo-controlled clinical trial

The authors hypothesized that H 2 O 2 formation in the mitochondria results in the inactivation of ATG4, promoting ATG8 lipidation, and thus, activation of autophagy