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A Phase 2 trial (Obesity Research, 2004) found 12 weeks of subcutaneous AOD-9604 produced statistically significant abdominal fat reduction versus placebo without altering fasting glucose or insulin levels

Plasma SAM was slightly higher at the end of the trial compared to baseline, both for individuals on VD and MD, and yet these variations fall within the reference range for healthy individuals

Moon HS, Thiruvengadam M, Chi HY, Kim B, Prabhu S, Chung IM, Kim SH (2024) Comparative study for metabolomics, antioxidant activity, and molecular docking simulation of the newly bred Korean red rice accessions

[DOI] [PubMed] [Google Scholar] 106.Jelnes P, Santoni-Rugiu E, Rasmussen M, Friis SL, Nielsen JH, Tygstrup N, Bisgaard HC