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10.1038/s41419-018-0374-7 127 LiuS.LiY.ChoiH

In controlled laboratory research environments, it is extensively studied for its involvement in cellular growth pathways, protein synthesis regulation, and peptide-mediated signaling networks

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Results from the phase 2 TROPION-Lung05 trial published in the Journal of Clinical Oncology revealed that among 137 patients given 6 mg/kg of dato-DXd every 21 days for pretreated NSCLC, the confirmed ORR was 35.8% (95% CI, 27.8%-44.4%), including 32.8% of patients experiencing a partial response and 2.9% having a complete response