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Copy number variants Copy number variants correspond to regions of the genome that have been deleted or duplicated on certain chromosomes

They define PCOS as the presence of two out of three criteria: hyperandrogenism (elevated levels of male hormones, assessed clinically -presence of acne, hirsutism- or biochemically), ovulatory dysfunction (oligo/anovulation, infrequent or absent ovulation), and/or polycystic ovarian morphology on ultrasound: either the presence of 20 or more follicles on a single ovary or ovarian volume above 10 cm3