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doi: 10.3389/fphar.2026.1755175 Received 26 November 2025 Revised 21 January 2026 Accepted 20 February 2026 Published 09 March 2026 Volume 17 - 2026 Edited by Roland Bcker, Charit University Medicine Berlin, Germany Reviewed by Mark Lloyd Dapar, Central Mindanao University, Philippines Kishor Jain, Sinhgad Institutes, India Updates Copyright 2026 Kayesh, Kohara and Tsukiyama-Kohara

As levels drop, inflammation can become more chronic and harder to manage

Nerve changes from a prolonged B12 deficiency can affect coordination and balance, leaving some people feeling unsteady, dizzy, or more prone to stumbling

Immune Function: Adequate glutathione levels support optimal immune cell function, which is particularly important for managing liver inflammation and preventing progression of liver disease