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Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice

[DOI] [PubMed] [Google Scholar] 563.Holm L, Cassidy JD, Carroll LJ, Borg J

The ANLS hypothesis draws heavily on data from techniques that measure metabolites and oxygen directly in the brain parenchyma (e.g., microsensors, microdialysis), emphasizing the rapid dynamics of a local lactate and oxygen pool (Hu and Wilson, 1997