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Description

Fukushima N et al (2016) Small-molecule hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells

They activate autoreactive T cells, which, in turn, release inflammatory cytokines [Interferon Gamma (IFN-), Tumor Necrosis Factor (TNF), Interleukin 17 (IL-17)] and engage in CTL-mediated killing