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The table below summarizes some of the available treatment options that have shown potential in experimental models and their clinical status (Table 1)

Neuron 105, 10771093 e7

Le glutathion est gnralement synthtis dans le foie partir de ses acides amins constitutifs

As a result, NRF2 is freed from Keap1, with which it forms a complex, and is translocated into the nucleus where it binds to antioxidant responsive elements (AREs) in the promoters of target genes (Fig