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Clinical trials demonstrate considerable weight loss in patients with obesity or Type 2 diabetes

For example, mutations in STXBP1 are associated with development (Saitsu et al., 2008

Importantly, we also evaluate the landscape of candidate ferroptosis-related biomarkers, which are indispensable for clinical translation, and discuss the major challenges that must be addressed to advance ferroptosis-targeted interventions from preclinical models to patient care